Note: Registrants can also select ‘other’ as the unit of measure. Registrants can register their substance explosiveness as: This section summarises the oxidising values from all registered dossiers for the substance. The purpose of the information provided under this section is to highlight in a readable format the substance hazardousness. Typically phthalate esters are prepared from the widely available phthalic anhydride. Biodegradation in water - screening tests, Biodegradation in water & sediment - simulation tests. The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Regulatory process names gives the names under which the substance appears in ECHA's regulatory processes and lists. 4 0. pH provides substance information on the substance’s acidity level measured in pH at a temperature measured in °C and a concentration measured in (milli)grams per litre. LC50 for marine water algae provides substance information on the substance’s lethal concentration for 50% of the marine water algae in the test, generally displayed in milligram per litre. More information about the EC Inventory can be found here. Based on given acidity constants (pK a values) the pH of organic acids for 1, 10, and 100 mmol/L are calculated.The results are listed in the following tables (valid for standard conditions 25°C, 1 atm):. 2006 Dec;5(12):993-6. Processable data for summary is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Oxidising. Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below. phthalic acid has 2 Kas since it is diprotic.. Ka1 = 1.3 X 10^-3. Harmonised classifications (√ - check mark). Perrin, D. D., Dissociation Constants of Organic Bases in Aqueous Solution, Butterworths, London, 1965; Supplement, 1972. organic acids – sorted by formula EC50/LC50 for marine sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the marine sediment, generally displayed in milligrams per kilogram (dry weight). Pesticide properties for Phthalic acid, including approvals, environmental fate, eco-toxicity and human health issues Bioaccumulation factor (aquatic species) provides substance information on the substance’s bioaccumulative properties not taking account the dimensions. Danger! This substance is used in formulation or re-packing, at industrial sites and in manufacturing. ThOD provides substance information on the substance’s ThOD values displayed in O2 (milli)gram per gram test material. Dipotassium phthalate. Epub 2013 Jul 11. ... Phthalic Acid – C. 8 H 6 O 4 2.9, 5.4 1.9-6.4 . Information on the most sensitive study can be provided by the registrants as: Dermal exposure provides information on the substance’s hazard assessment conclusions regarding dermal exposure (for workers). The brief profile is based on non-confidential data contained in ECHA’s databases at the time of generation. If more than one result with the same value, data is further prioritised by test type and endpoint conclusion. See ‘Summary oral systemic effects’, except: ‘See Summary inhalation systemic effects’. More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header . Manufacturers and importers can provide the following information in the registration dossier: Hazard for Air provides information on the substance’s hazard assessment conclusion related to air. If so, the data provided is not processed for the Brief Profile. See information under ‘Applicant’s summary and conclusion – interpretation of results (oral)’. Nam ante ipsum, suscipit non sapien nec, congue consequat ante. Registrants can identify the origin of their substance as being: If more than one type of substance is registered, both types will be displayed. Data generally displayed in milligrams per kilogram bodyweight per day. Phototransformation in water provides information on the substance’s phototransformation in water in seconds/minutes/hours/days/weeks/months/years. The CLP regulatory processes identified for the Brief Profile are: The BPR (528/2012) entered into force on 1 September 2013. Please upgrade your Internet Explorer to a newer version. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information. This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. To have more information on impurities relevant to classification you can consult the C&L Inventory entry for the substance, or the disseminated registration dossier. A substance may have more than one CAS number associated. Half-life in soil provides substance information on the substance’s half-life in water in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C. level’ as the dose descriptor. When more than one numerical result is available per endpoint the count is displayed between square brackets. Data is generally standardised and displayed in milligram per litre or molar per litre. (NTP, 1992). If so, the data provided is not processed for the Brief Profile. Registrants can register their substance oxidising properties as: This section summarises the oxidation reduction potential values from all registered dossiers for the substance. If so, the data provided is not processed in the Brief Profile. A recent food safety concern has arisen from the unapproved use of certain phthalates in a broad range of food/nutraceutical ingredients from Taiwan [53]. EC/LC50 for freshwater plants provides substance information on the substance’s effect concentration or lethal concentration for 50% of the freshwater plants in the test, generally displayed in milligram per litre. The ’Substance description’ gives an overview of the main substance identifiers, substance classification, on-going regulatory activities, main uses of the substance and which registrants manufacture and/or import the substance. This section summarises the Ecotoxicological information provided from all registered dossiers for the substance. Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Different classifications can also be due to technical errors made during the notification process. This section summarises the values related to long term toxicity to fish from all registered dossiers for the substance. The number of studies provided is indicated by ‘[x] studies submitted’, while the actual number of studies processed for the endpoint is indicated by ‘[x] studies processed’. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH). If more than one numerical result is available per endpoint, the range of results (min-max) will be presented (RANGE method). 2003 Aug;306(2):703-8. This section summarises the values related to toxicity to (terrestrial) plants from all registered dossiers for the substance. Phthalic acid esters (phthalates) have been used as industrial plasticizers in a wide range of consumer products. PNEC sediment, data displayed in milligram per kilo sediment (dry weight). If information on guidance on safe use is available in REACH registered dossiers, a link is displayed. The availability of additional data beyond the five results displayed is indicated by (…).Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). The Agency thus cannot guarantee the correctness of the information displayed. If so, the data provided is not processed for the Brief Profile. InChIs consist of text strings comprising different layers and sublayers of information separated by slashes (/). CAS names gives the name(s) provided to ECHA by the Chemical Abstracts Service, a division of the American Chemical Society, where available. 4409-98-7. The dark blue bar illustrates the percentage of matching substance classifications provided by manufacturers and importers in a REACH registration dossier. Values are displayed in milligram per litre. 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